The artist has handed over the complete sum of his £25,000 Mercury Prize cash to the trust for venues, which works to preserve the UK's independent live music spots.
He was awarded the cheque on October 16 as his latest record his work was named the outstanding release of the previous year.
Fender has opted to donate the funds to the Music Venues Trust, in recognition of the vital role small stages played in his initial steps.
"I personally couldn't be pursuing my current career if it wasn't for all the performances I played around the North East, and beyond, when I was starting out," stated the artist. "These spaces are iconic, but they are struggling."
From early 2023 onward, over 150 of these venues have ceased operations – about 16 percent of the total UK scene.
In the last year, top acts like Pulp, the group Coldplay, Katy Perry and Ed Sheeran have all supported the Music Venues Trust in its attempts to help venues survive, by adding a small levy to their admission fees, which benefits smaller concert halls.
Sam Fender also took part, generating in excess of £100,000 on his live tour to support thirty-eight local spots across England, Scotland, and Wales.
The donation helped locations that were dealing with possible closure due to issues arising from floods, fires and bereavements, as well as licensing issues, conflicts and neighbor objections.
Some locations were granted funding support in upgrading amenities and technical equipment that helped musicians and audiences.
"The concept that revenue from shows in big venues backs the local stages, where it kicks off for performers like me, is just common sense," Sam Fender has said.
Fender is not the first artist to give his Mercury Prize funds to worthy causes.
Back when Pulp won the trophy in the mid-90s for their record their work, vocalist the singer declared that the band would contribute their cash to the organization War Child.
During 2002, rapper and singer she divided her prize between several good causes, including the children's charity and a Sickle Cell charity.
"And I gave a £1,000 to the center, to their classes, because I practiced gymnastics when I was younger and they required better apparatus," Ms Dynamite explained to the media.
Two years ago, the band donated their prize money to the local youth club that nurtured their act, in addition to other grassroots music organisations.
And winners that year the group donated their award to a MS organization after a close contact was found to have the illness.
"Receiving the award was sufficient," remarked vocalist Heather Small. "The prize was the extra but we could do without the cherry, because we had the main prize. So our success touched another person's life."
Last week, the Music Venues Trust announced it had protected several local spots in south-east England, by placing them under public stewardship.
The Joiners in the city and the other in Bristol were acquired under the public acquisition program, which is funded by Arts Council England and enthusiasts who buy "ownership units" in the venues.